Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

This is a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung cancer

Trial Details

NCT ID
NCT04614103
Phase
PHASE2
Sponsor
Iovance Biotherapeutics, Inc.
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • LN-145
Locations (sample)
  • Gilbert, Arizona, United States|33.35283,-111.78903
  • Duarte, California, United States|34.13945,-117.97729
  • La Jolla, California, United States|32.84727,-117.2742
  • Los Angeles, California, United States|34.05223,-118.24368
  • Newark, Delaware, United States|39.68372,-75.74966

Key Eligibility Criteria

  • Patients who are over 70 years of age may be allowed to enroll after discussion with the Medical Monitor.
  • Have historically or pathologically confirmed diagnosis of metastatic Stage IV NSCLC without EGFR, ALK, or ROS1 genomic alterations.
  • For patients who have actionable mutations (other than EGFR, ALK, or ROS1 genomic alterations), 1 additional line of therapy with the appropriate h…
  • Patients must have documented radiographic disease progression on or after the first-line therapy, including concurrent or sequential ICI and plati…

For full eligibility, visit ClinicalTrials.gov.

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