CAR-T Cells Combined With Dasatinib for Patients With Relapsed and/or Refractory B-cell Hematological Malignancies

A Study of CD19/BCMA-targeted CAR-T Cells Combined With Dasatinib for Patients With Relapsed and/or Refractory B-cell Acute Lymphoblastic Leukemia, B-cell Non-Hodgkin's Lymphoma and Multiple Myeloma.

Trial Details

NCT ID
NCT04603872
Phase
EARLY_PHASE1
Sponsor
Zhejiang University
Status
RECRUITING
Cancer Type
Multiple Myeloma
Interventions
  • CD19/BCMA Targeted CAR T-cells and dasatinib
  • CD19/BCMA Targeted CAR T-cells
Locations (sample)
  • Hangzhou, Zhejiang, China|30.29365,120.16142

Key Eligibility Criteria

  • Histologically confirmed diagnosis of CD19+ ALL, CD19+ NHL, or BCMA+ MM per the US National Comprehensive Cancer Network (NCCN) Clinical Practice G…
  • Relapsed or refractory B cell hematological malignancies (meeting one of the following conditions):
  • CR not achieved after standardized chemotherapy;
  • CR achieved following the first induction, but CR duration is less than 12 months;

For full eligibility, visit ClinicalTrials.gov.

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