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NCT04494503
Study of APG2575 Single Agent and Combination Therapy in Patients With Relapsed/Refractory CLL/SLL
The purpose of this study is to assess the safety, pharmacokinetic, pharmacodynamic and efficacy of APG-2575 single agent and in combination with other therapeutic agents in patients with relapsed/refractory CLL/SLL.
Trial Details
NCT ID NCT04494503
Phase PHASE1 / PHASE2
Sponsor Ascentage Pharma Group Inc.
Status RECRUITING
Cancer Type Lymphoma
Interventions APG-2575 Rituximab Ibrutinib
Locations (sample) Beijing, Beijing Municipality, China|39.9075,116.39723 Chongqing, Chongqing Municipality, China|29.56026,106.55771 Guangzhou, Guangdong, China|23.11667,113.25 Nanning, Guangxi, China|22.81667,108.31667 Guiyang, Guizhou, China|26.58333,106.71667
Key Eligibility Criteria
Subjects who meet each of the following inclusion criteria are eligible to participate in this study: Age ≥18 years old. Diagnosis as relapsed/refractory chronic lymphocytic leukemia/ small lymphocytic lymphoma according to the IWCLL NCI-WG guidelines revised in 2008. Through radiological assessment, subjects with a lymph node length ≥ 10 cm require prior approval from the sponsor before enrollment.
For full eligibility, visit ClinicalTrials.gov .
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