Multi-4SCAR-T Therapy Targeting Breast Cancer

The purpose of this study is to assess the feasibility, safety and efficacy of multiple 4th generation CAR-T cells targeting Her2, GD2, and CD44v6 surface antigen in breast cancer. Another goal of the study is to learn more about the activities of the multi-CAR T cells and their persistency in the patients.

Trial Details

NCT ID

NCT04430595

Phase

PHASE1 / PHASE2

Sponsor

Shenzhen Geno-Immune Medical Institute

Status

RECRUITING

Cancer Type

Breast Cancer

Interventions

4SCAR T cells

Locations (sample)

Shenzhen, Guangdong, China|22.54554,114.0683

Key Eligibility Criteria

Patients with stage III, IV or relapsed breast cancer confirmed by histology and biopsy.
Age: ≥ 18 years and ≤ 75 years.
2 weeks at least since last chemotherapy or radiotherapy and 2 weeks at least since last systemic steroid hormone and other immunosuppressive therapy.
Side effects of chemotherapy have subsided.

For full eligibility, visit ClinicalTrials.gov.

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