Plasma Radiofrequency Ablation at Low Temperature Versus Electrocautery Block Resection at High Frequency for Localized Recurrent Nasopharyngeal Carcinoma

This study aims at exploring whether plasma radiofrequency ablation at low temperature is associated with better survival outcome in localized recurrent nasopharyngeal carcinoma by conducting a randomized controlled trial of plasma radiofrequency ablation at low temperature versus electrocautery block resection at high frequency for localized recurrent nasopharyngeal carcinoma. If the hypothesis is confirmed, it is expected to provide a convenient choice for the surgical treatment of localized recurrent nasopharyngeal carcinoma.

Trial Details

NCT ID
NCT04425265
Phase
NA
Sponsor
Sun Yat-sen University
Status
RECRUITING
Cancer Type
Nasopharyngeal Head and Neck Cancer
Interventions
  • Plasma radiofrequency ablation
  • Electrocautery block resection
Locations (sample)
  • Guangzhou, Guangdong, China|23.11667,113.25
  • Zhuhai, Guangdong, China|22.27694,113.56778
  • Nanchang, Jiangxi, China|28.68396,115.85306

Key Eligibility Criteria

  • At least 6 months disease free interval (defined as duration between the initial course of radiotherapy and recurrence)
  • Histopathologically diagnosed with undifferentiated or differentiated, nonkeratinizing nasopharyngeal carcinoma.
  • Resectable recurrent nasopharyngeal carcinoma: rT1-3N0-3M0 A) The tumor is confined to the nasopharyngeal mucosa, or the surface of the parapharyng…
  • Age: 18-70 years old.

For full eligibility, visit ClinicalTrials.gov.

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