Personalized Second Chance Breast Conservation (PSCBC): A Prospective Phase II Clinical Study

The goal of the study is to investigate the feasibility of enabling a second chance for breast conservation in patients with in-breast recurrences after a previous lumpectomy and RT, investigators propose to test partial breast irradiation with the target volume encompassing the entire surgical bed with 1.0-1.5 cm margins. An additional goal of the study is to investigate the feasibility of enabling a second chance for breast conservation in patients with inbreast recurrences after a previous lumpectomy and PBI, the investigators propose to test whole breast RT (WBRT) with the target as the w

Trial Details

NCT ID
NCT04371913
Phase
NA
Sponsor
Weill Medical College of Cornell University
Status
RECRUITING
Cancer Type
Breast Cancer
Interventions
  • 600cGY x 5 fractions APBI
  • 270cGy x 15 fractions WBRT
Locations (sample)
  • Brooklyn, New York, United States|40.6501,-73.94958
  • New York, New York, United States|40.71427,-74.00597
  • New York, New York, United States|40.71427,-74.00597

Key Eligibility Criteria

  • Isolated ipsilateral unifocal breast lesions
  • Limited size (\< 2-3 cm) without evidence of skin involvement
  • Histologically proven invasive breast carcinoma or carcinoma in situ
  • Negative histologic margins of resection

For full eligibility, visit ClinicalTrials.gov.

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