UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial Lesions

In this proposal, the investigators introduce advanced diffusion and volumetric imaging techniques along with innovative, automated image parcellation methods to identify critical brain regions, incorporate into cognitive-sparing SRS for intracranial lesions, and analyze biomarkers of radiation response. This work will advance the investigators' understanding of neurocognitive changes after brain SRS and help create interventions that preserve cognitive-function in patients with intracranial lesions.

Trial Details

NCT ID
NCT04343157
Phase
PHASE2
Sponsor
Jona Hattangadi-Gluth
Status
RECRUITING
Cancer Type
Brain Cancer
Interventions
  • Cognitive Sparing Brain Stereotactic Radiosurgery (SRS)
Locations (sample)
  • San Diego, California, United States|32.71571,-117.16472

Key Eligibility Criteria

  • Patients 18 years or older
  • Eligible for intracranial SRS: Limited brain metastases targets geometrically feasible for SRS (intact or resected tumor bed), meningioma, or cereb…
  • Eastern cooperative Oncology Group (ECOG) performance status 0-2 (score of 0, no symptoms; 1, mild symptoms; 2, symptomatic, \<50% in bed during th…
  • Ability to answer questions and follow commands via neurocognitive testing

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Brain Cancer Trials on Trialify →