Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma

The goal of this randomized phase II study is a formal comparison of radiotherapy versus trans-oral surgery as the primary treatment of HPV-negative patients with early-stage oropharyngeal carcinoma.

Trial Details

NCT ID
NCT04220749
Phase
PHASE2
Sponsor
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Status
RECRUITING
Cancer Type
Head and Neck Cancer
Interventions
  • Radiation
  • Trans-Oral Surgery (TOS) + Neck Dissection
Locations (sample)
  • London, Ontario, Canada|42.98339,-81.23304

Key Eligibility Criteria

  • Age 18 years or older
  • Willing to provide informed consent
  • ECOG performance status 0-2
  • Histologically confirmed squamous cell carcinoma

For full eligibility, visit ClinicalTrials.gov.

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