LITT Followed by Hypofractionated RT for Recurrent Gliomas

The purpose of this study is to evaluate the treatment regimen of using Laser Interstitial Thermal Therapy (LITT) and Hypo-fractionated Radiation Therapy to treat patients with recurrent gliomas.

Trial Details

NCT ID
NCT04181684
Phase
NA
Sponsor
University of Maryland, Baltimore
Status
RECRUITING
Cancer Type
Glioblastoma (GBM) Brain Cancer
Interventions
  • Procedure: LITT
  • Hypo-Fractionated Radiation Therapy
Locations (sample)
  • Baltimore, Maryland, United States|39.29038,-76.61219
  • Bel Air, Maryland, United States|39.53594,-76.34829
  • Columbia, Maryland, United States|39.24038,-76.83942
  • Glen Burnie, Maryland, United States|39.16261,-76.62469

Key Eligibility Criteria

  • Patients with history of a WHO Grade II-IV glioma with radiographic evidence of recurrent or progressive tumor
  • Patient must have received prior radiation therapy for initial treatment of glioma
  • Patients with any number of recurrences are allowed as long as the patient has not undergone re-irradiation
  • Brain MRI with contrast demonstrates an enhancing tumor ≤ 6 cm in largest diameter within 60 days prior to registration

For full eligibility, visit ClinicalTrials.gov.

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