Pemetrexed and Carboplatin With or Without Anlotinib Hydrochloride for Osimertinib-resistant Non-squamous NSCLC

Evaluate the efficacy and safety of Anlotinib Hydrochloride in combination with Pemetrexed and Carboplatin versus Pemetrexed and Carboplatin for advanced or locally-advanced Osimertinib-resistant non-squamous non-small cell lung cancer.

Trial Details

NCT ID
NCT04136535
Phase
PHASE2
Sponsor
Fudan University
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Pemetrexed
  • Carboplatin
  • Anlotinib
Locations (sample)
  • Shenzhen, shenzhen, China|22.54554,114.0683

Key Eligibility Criteria

  • 1\. 18 Years to 75 Years patients voluntarily participate in this study, signed and dated informed consent with good compliance and follow-up; 2. C…
  • Blood routine examination criteria (no blood transfusion and blood products within 14 days, no correction by G-CSF and other hematopoietic stimuli):
  • i) hemoglobin (HB) ≥90g/L ii) neutrophil absolute (ANC) ≥1.5×109/L iii) platelet (PLT) ≥80×109/L Biochemical tests meet the following criteria i) t…
  • Female patients of childbearing age agree that contraceptive measures must be used within the study period and within 8 weeks after the end of the …

For full eligibility, visit ClinicalTrials.gov.

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