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NCT04136535
Pemetrexed and Carboplatin With or Without Anlotinib Hydrochloride for Osimertinib-resistant Non-squamous NSCLC
Evaluate the efficacy and safety of Anlotinib Hydrochloride in combination with Pemetrexed and Carboplatin versus Pemetrexed and Carboplatin for advanced or locally-advanced Osimertinib-resistant non-squamous non-small cell lung cancer.
Trial Details
NCT ID NCT04136535
Phase PHASE2
Sponsor Fudan University
Status RECRUITING
Cancer Type Lung Cancer
Interventions Pemetrexed Carboplatin Anlotinib
Locations (sample) Shenzhen, shenzhen, China|22.54554,114.0683
Key Eligibility Criteria
1\. 18 Years to 75 Years patients voluntarily participate in this study, signed and dated informed consent with good compliance and follow-up; 2. C… Blood routine examination criteria (no blood transfusion and blood products within 14 days, no correction by G-CSF and other hematopoietic stimuli): i) hemoglobin (HB) ≥90g/L ii) neutrophil absolute (ANC) ≥1.5×109/L iii) platelet (PLT) ≥80×109/L Biochemical tests meet the following criteria i) t… Female patients of childbearing age agree that contraceptive measures must be used within the study period and within 8 weeks after the end of the …
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