ESD for Colorectal LSL Using a Selective Strategy - a Prospective Cohort Study

Colonic Laterally spreading lesions (LSL) =\> 20mm are at high risk to progress to cancer. Overt stigmata of submucosal invasive cancer (SMIC) has been well characterized and includes ulceration and surface pit pattern changes as per the Kudo classification of type V. In a recent report, risk factors for LSL with SMIC and no overt stigmata (i.e. covert SMIC) were described. Resection of these lesions 'en-bloc' can allow for better histological staging and potentially reduce the need for surgical resection.

Trial Details

NCT ID
NCT04008407
Phase
NA
Sponsor
Western Sydney Local Health District
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • Endoscopic Submucosal Dissection
  • Endoscopic Mucosal Resection
Locations (sample)
  • Westmead, New South Wales, Australia|-33.80383,150.98768

Key Eligibility Criteria

  • All patients referred for colorectal resection of large laterally spreading lesions in colon.
  • Can give informed consent to trial participation

For full eligibility, visit ClinicalTrials.gov.

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