Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

This phase II trial studies how well low-dose radiotherapy works in treating bone pain in patients with multiple myeloma that has spread to the bone. Radiation therapy uses high energy x-rays, gamma rays, neutrons, protons, or other sources to kill tumor cells and shrink tumors. Low-dose radiotherapy may be more convenient for patients and their families, may not interfere as much with the timing of chemotherapy, and may have less chance for short term or long-term side effects from the radiation.

Trial Details

NCT ID
NCT03858205
Phase
NA
Sponsor
University of Southern California
Status
RECRUITING
Cancer Type
Multiple Myeloma
Interventions
  • Quality-of-Life Assessment
  • Questionnaire Administration
  • Radiation Therapy
Locations (sample)
  • Duarte, California, United States|34.13945,-117.97729
  • Los Angeles, California, United States|34.05223,-118.24368
  • Los Angeles, California, United States|34.05223,-118.24368
  • Los Angeles, California, United States|34.05223,-118.24368
  • Atlanta, Georgia, United States|33.749,-84.38798

Key Eligibility Criteria

  • Histologic diagnosis of multiple myeloma
  • Painful bone metastasis (index lesion) that has a radiographic correlate
  • Patient may have had any number of prior chemotherapy/immunotherapy regimens (changes to systemic therapy or use of bisphosphonates for 4 weeks bef…
  • Eastern Cooperative Oncology Group (ECOG) 0-2

For full eligibility, visit ClinicalTrials.gov.

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