Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases

Nearly one third of patients with colorectal cancer develop liver metastases. It is well known that the achievement of a R0-situation is one of the most important factors for a positive long-term outcome. Despite further advantages in multimodal treatment concepts, only 20 - 30 % of the patients with metastases can be resected in curative intention. Recent studies, especially from Norway, have shown that liver transplantation might be a feasible option in well selected patients since the complete hepatectomy with subsequent liver transplantation can be an option for the achievement of a R0 si

Trial Details

NCT ID

NCT03488953

Phase

NA

Sponsor

Jena University Hospital

Status

RECRUITING

Cancer Type

Colorectal Cancer

Interventions

• Living donor liver transplantation with two-staged hepatectomy.

Locations (sample)

• Jena, Germany|50.92878,11.5899
• Tübingen, Germany|48.52266,9.05222

Key Eligibility Criteria

• Patients with irresectable colorectal liver metastases without extrahepatic tumor burden, except resectable pulmonary metastases
• stable disease or regression after at least eight weeks of systemic chemotherapy

For full eligibility, visit ClinicalTrials.gov.

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