Partial Prostate Salvage High Dose Rate Brachytherapy

A dose-response relationship for radiation in the management of prostate cancer is well established. Local recurrence of prostate cancer after external beam radiotherapy occurs in at least 40% of patients treated because of inability to deliver sufficient dose through external beam techniques. These patients respond well to re-irradiation using brachytherapy with about 50% of selected patients remaining free of recurrence 5 years after salvage. Advanced imaging using multiparametric Magnetic Resonance Imaging (mpMRI) allows identification of the site of recurrence, permitting partial prostate

Trial Details

NCT ID
NCT03246802
Phase
NA
Sponsor
British Columbia Cancer Agency
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • HDR partial prostate brachytherapy
Locations (sample)
  • Kelowna, British Columbia, Canada|49.88307,-119.48568

Key Eligibility Criteria

  • Age \>45 and Life expectancy \>10 years
  • Previous External Beam Radiotherapy (EBRT) or LDR brachytherapy w
  • \> 3 year interval since EBRT or LDR Brachytherapy
  • No late toxicity from prior EBRT ≥ grade 2

For full eligibility, visit ClinicalTrials.gov.

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