Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome

The main objective will be to check if MyoInositol (MYO) reduces the total resistance rate to Clomiphene Citrate (CC). For this, our study will be controlled, randomized and double blinded. It will include patients with PCOS (polycystic ovary syndrome, defined by the Rotterdam criteria) who wish to become pregnant and are eligible to simple ovulation induction by CC. Half of them will receive MYO + levomefolic acid (5-MTHF) in addition to the CC, while the other half will receive a placebo containing only 5-MTHF in addition to the CC. The MYO supplementation will be initiated at least one mont

Trial Details

NCT ID
NCT03059173
Phase
PHASE3
Sponsor
University Hospital, Lille
Status
RECRUITING
Cancer Type
Ovarian Cancer
Interventions
  • Myo-Inositol + Levomefolic acid
  • Clomiphene Citrate
  • placebo
Locations (sample)
  • Lille, France|50.63391,3.05512

Key Eligibility Criteria

  • Wishing pregnancy,
  • Having PCOS defined by the Rotterdam criteria: high antral follicle count (AFC) (\> 19 per ovary) and/or a disorder of the cycle and/or hyperandrog…
  • Having never been treated with CC (or previous treatment with CC interrupted for \> 3 months).
  • Having received complete information and having signed consent.

For full eligibility, visit ClinicalTrials.gov.

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