Comparison of Proton and Photon Radiotherapy of Brain Tumors (ProtoChoice-Hirn)

This protocol compares the toxicity of radiotherapy or radiochemotherapy applied with different radiation modalities - protons or photons. Patients with different kinds of brain tumours and foreseen high-dose radiotherapy can be included. The hypothesis of the trial is that the rate of chronic toxicity 1 year after the end of radiotherapy is 15% lower after proton compared to photon treatment.

Trial Details

NCT ID
NCT02824731
Phase
NA
Sponsor
Technische Universität Dresden
Status
RECRUITING
Cancer Type
Brain Cancer
Interventions
  • Radiation with protons
  • Radiation with photons
Locations (sample)
  • Dresden, Germany|51.05089,13.73832
  • Marburg, Germany|50.80904,8.77069

Key Eligibility Criteria

  • primary brain tumor: gliomas (low or high grade), intracerebral meningiomas, pituitary adenomas, craniopharyngioma and other rare brain tumors or
  • brain tumor recurrence without pre-irradiation or
  • brain tumor recurrence with pre-irradiation \> 40 Gy in the overlap region with the recurrence region
  • indication for radiotherapy or radiochemotherapy

For full eligibility, visit ClinicalTrials.gov.

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