Acupuncture or Metformin for Insulin Resistance in Women With PCOS

The hypothesis is that acupuncture is equally effective as metformin (both treatments combined with lifestyle management) in improving whole body glucose homeostasis in insulin resistant women with polycystic ovary syndrome (PCOS), and that both are superior to lifestyle management alone. The investigators hypothesize that acupuncture and metformin induce ovulation and improve hyperandrogenism, as well as health related quality of life (HRQoL) and symptoms of anxiety and depression. Although equally effective (acupuncture and metformin), the investigators hypothesize that acupuncture is associ

Trial Details

NCT ID

NCT02647827

Phase

PHASE2

Sponsor

Karolinska Institutet

Status

RECRUITING

Cancer Type

Ovarian Cancer

Interventions

Lifestyle management
Acupuncture
Metformin

Locations (sample)

Beijing, China|39.9075,116.39723
Stockholm, Sweden|59.32938,18.06871

Key Eligibility Criteria

Age 18 to 40 years
Body mass index (BMI) ≥25 to ≤40 given that 95% of all women with PCOS with a BMI ≥25 are insulin resistant (71,72).
PCOS diagnosis according to Rotterdam criteria 2003 (73), with at least two of the following three symptoms: Clinical signs of hyperandrogenism (hi…
Willing to sign the consent form.

For full eligibility, visit ClinicalTrials.gov.

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