Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

The ALL SCTped 2012 FORUM is a multinational, multi-centre, controlled, prospective phase III study for the therapy and therapy optimisation for children and adolescents with ALL in complete morphological remission (CR, less than 5% bone marrow blasts, no blasts in cerebrospinal fluid, no other extramedullary leukemia), who have an indication for HSCT with a myeloablative conditioning regimen. The stratification of patients in first and following remissions according to the individual transplantation modalities rests upon an indication for allogeneic HSCT and the availability of a suitable do

Trial Details

NCT ID

NCT01949129

Phase

PHASE2 / PHASE3

Sponsor

St. Anna Kinderkrebsforschung

Status

RECRUITING

Cancer Type

Leukemia

Interventions

VP16
TBI
Thiotepa
Treosulfan
Fludarabine
Busulfan

Locations (sample)

Buenos Aires, Argentina|-34.61315,-58.37723
La Plata, Argentina|-34.92126,-57.95442
Melbourne, Australia|-37.814,144.96332
Perth, Australia|-31.95224,115.8614
Randwick, Australia|-33.91439,151.24895

Key Eligibility Criteria

Patients with ALL (except for patients with B-ALL) who fulfil the following criteria:
age at diagnosis ≤ 18 years. Age at HSCT ≤ 21 years
indication for allogeneic HSCT
complete remission (CR) before HSCT

For full eligibility, visit ClinicalTrials.gov.

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